50 YEARS OF ANTIBODY NUMBERING SCHEMES: A STATISTICAL AND STRUCTURAL EVALUATION REVEALS KEY DIFFERENCES AND LIMITATIONS

50 Years of Antibody Numbering Schemes: A Statistical and Structural Evaluation Reveals Key Differences and Limitations

Background: The complementarity-determining region (CDR) of antibodies represents the most diverse region both in terms of sequence and structural characteristics, playing the most critical role in antibody recognition and binding for immune responses.Over the past decades, several numbering schemes have been SKINCARE TOOL introduced to define CDRs

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Mechanisms of GII.4 norovirus persistence in human populations.

Noroviruses are the leading cause of viral acute gastroenteritis in humans, noted for causing epidemic outbreaks in communities, the military, cruise ships, hospitals, and assisted living communities.The evolutionary mechanisms governing the persistence and emergence of new norovirus strains in human populations are unknown.Primarily organized by s

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